⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7200266 | 0.98 | — | — | |
| SCHEMBL2575298 | 0.83 | — | — | |
| SCHEMBL28171928 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL4437211 | 0.75 | GRIA1 (0.36) | — | |
| Aspartic Acid SCHEMBL5964784 | 0.70 | GRIA1 (0.43) | — | |
| SCHEMBL5281708 | 0.63 | GRIA1 (0.49) | — | |
| SCHEMBL9548280 | 0.63 | NOTUM (0.40) | — | |
| SCHEMBL12648359 | 0.63 | GRIA1 (0.49) | — | |
| SCHEMBL13319909 | 0.63 | GRIA1 (0.41) | — | |
| SCHEMBL5290687 | 0.63 | GRIA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3197 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250354-A1 | NEW CLASS OF MOLECULES FOR SELECTIVE CLEARANCE OF ANTIBODY | OSE IMMUNOTHERAPEUTICS (FR) | 2025-08-07 | — | — | US | claimed |
| US-20250213564-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER NEUROGENERATIVE DISEASE | THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. | 2025-07-03 | — | — | US | claimed |
| EP-4577305-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER NEUROGENERATIVE DISEASE | 1/1THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-07-02 | — | — | EP | claimed |
| CN-119487066-A | Targeted protein degradation system and application thereof | 羿尊生物医药（浙江）有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119233999-A | Fusion protein of targeting cell membrane receptor protein and application thereof | 羿尊生物医药（浙江）有限公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4463138-A1 | MULTI-VESICULAR LIPID NANOPARTICLE TOLEROGENIC VACCINES FOR INDUCTION OF SYSTEMIC IMMUNE TOLERANCE IN VIVO | Karma Biotechnologies (US) | 2024-11-20 | — | — | EP | claimed |
| WO-2023137227-A9 | MULTI-VESICULAR LIPID NANOPARTICLE TOLEROGENIC VACCINES FOR INDUCTION OF SYSTEMIC IMMUNE TOLERANCE IN VIVO | KARMA BIOTECHNOLOGIES (US) | 2024-07-11 | — | — | WO | claimed |
| EP-4392438-A2 | FLUORESCENT SENSOR FOR MONITORING CALCIUM DYNAMICS | Yang, Jenny (US) | 2024-07-03 | — | — | EP | claimed |
| CN-118103389-A | Fluorescent sensor for monitoring calcium kinetics | J·杨 | 2024-05-28 | — | — | CN | claimed |
| WO-2024102177-A1 | COMBINATION THERAPIES FOR THE TREATMENT OF BRAIN CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-05-16 | — | — | WO | claimed |
| US-6083947-A | Method for treating sexual dysfunctions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-07-04 | — | — | US | claimed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | claimed |
| WO-2000024395-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | IKONOMIDOU HRISSANTHI (DE) | 2000-05-04 | — | — | WO | claimed |
| WO-2000001376-A2 | PHARMACEUTICAL COMPOSITIONS AND THEIR USES FOR TREATMENT OF DEMYELINATING DISORDERS | EISAI CO., LTD (JP) | 2000-01-13 | — | — | WO | claimed |
| EP-0918518-A1 | TREATMENT OF MOOD/AFFECTIVE DISORDERS BY GLUTAMATERGIC UPMODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1999021422-A1 | TREATMENT OF SCHIZOPHRENIA WITH AMPAKINES AND NEUROLEPTICS | CORTEX PHARMACEUTICALS, INC. (US) | 1999-05-06 | — | — | WO | claimed |
| WO-1997039750-A1 | TREATMENT OF MOOD/AFFECTIVE DISORDERS BY GLUTAMATERGIC UPMODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-10-30 | — | — | WO | claimed |
| US-5202257-A | Pure DNA which is capable of hybridizing with receptor polynucleotides under mild conditions | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1993-04-13 | — | — | US | claimed |
| EP-0497884-A1 | GLUTAMATE RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-08-12 | — | — | EP | claimed |
| WO-1991006648-A1 | GLUTAMATE RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1991-05-16 | — | — | WO | claimed |