Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19121353 | 0.91 | ALOX5 (0.44) | ALOX5LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL25497673 | 0.89 | ALOX5 (0.42) | ALOX5LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL13761352 | 0.87 | MAPT (0.49) | ALOX5LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL25753029 | 0.83 | ALOX5AP (0.42) | HPGDSCN9A | |
| SCHEMBL17732582 | 0.83 | ALOX5 (0.47) | ALOX5LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL16987331 | 0.81 | GPR27 (0.46) | ALOX5LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL15631138 | 0.80 | ALOX5 (0.51) | ALOX5LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL12506962 | 0.79 | GAA (0.50) | GAAHDAC1HDAC6 | |
| SCHEMBL23243628 | 0.78 | ALOX5 (0.46) | ALOX5LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL30721634 | 0.78 | MAOA (0.42) | ALOX5LMNAMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685731-B2 | Processes of preparing a JAK1 inhibitor | INCYTE CORPORATION (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685731-B2 | Processes of preparing a JAK1 inhibitor | JAK1, JAK2, JAK3 | ALOX5 1625/4885LMNA 4714/4885MAPT 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.