SCHEMBL257531

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9323609	0.84	ALDH1A1 (0.61)	HPGDCNR2MAPTHSD17B10ATM
	SCHEMBL257510	0.81	CYP1A2 (0.64)	HPGDCYP1A2CYP2C19CYP2D6CNR2
	SCHEMBL9360017	0.81	CYP1A2 (0.69)	HPGDCYP1A2CYP2C19CYP2D6MAPT
	SCHEMBL786726	0.81	HSD17B1 (0.46)	CYP1A2CYP2C19CNR2CYP3A4RXFP1
	SCHEMBL9343741	0.81	CA12 (0.63)	HPGDCYP1A2CYP2C19CYP2D6CNR2
	SCHEMBL2450750	0.81	TUBB4A (0.72)	HPGDCYP1A2CYP2C19CYP2D6TUBB4A
	SCHEMBL16260620	0.80	CA12 (0.62)	HPGDCNR2MAPTCYP3A4HSD17B10
	SCHEMBL12677654	0.80	PDE4A (0.45)	HPGDCYP1A2CYP2C19CYP2D6MAPT
	SCHEMBL12574135	0.78	CYP1A2 (0.56)	HPGDCYP1A2CYP2C19CYP2D6CYP3A4
	SCHEMBL1333620	0.77	CYP1A2 (0.81)	HPGDCYP1A2CYP2C19CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.