SCHEMBL25753191

SCHEMBL25753191

CNC(=O)COCNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)COCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)CC(C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CCKAR P32238 17/20 0.40
CCKBR P32239 14/20 0.40
OPRK1 P41145 2/20 0.40
OPRL1 P41146 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25969517 0.91 CCKAR (0.40) CCKARCCKBROPRK1OPRL1
SCHEMBL20345222 0.89 CCKAR (0.43) CCKARCCKBROPRK1OPRL1
SCHEMBL25752481 0.89 AKT1 (0.43) CCKARCCKBR
SCHEMBL25875278 0.88 OPRK1 (0.43) CCKARCCKBROPRK1OPRL1
SCHEMBL22969979 0.88 OPRL1 (0.40) OPRK1OPRL1
SCHEMBL26030700 0.87 ALDH1A1 (0.43) OPRL1
SCHEMBL25564745 0.86 OPRL1 (0.38) OPRK1OPRL1
SCHEMBL25871508 0.83 AKT1 (0.47) CCKARCCKBR
SCHEMBL25871152 0.83 AKT1 (0.45) CCKARCCKBR
SCHEMBL24823232 0.82 OPRL1 (0.43) OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685742-B2 Anti-tumor compound and preparation method and use thereof DUALITY BIOLOGICS (SUZHOU) CO., LTD. (CN) 2023-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685742-B2 Anti-tumor compound and preparation method and use thereof RCC2, REN, VHL CCKAR 876/4885CCKBR 1459/4885OPRK1 2298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.