Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | PYGL | P06737 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753458 | 0.85 | MAPT (0.55) | PTGS2CYP1A2CYP3A4PKMKDM4E | |
| SCHEMBL25753457 | 0.83 | MAOB (0.53) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL26248943 | 0.82 | MAPT (0.54) | CYP1A1CYP3A4CYP1B1PKMKDM4E | |
| SCHEMBL25753464 | 0.82 | PTGS2 (0.49) | PTGS2CYP1A1CYP1A2CYP1B1PKM | |
| SCHEMBL28497749 | 0.81 | JAK2 (0.56) | CYP3A4CYP2D6ABCG2PKMKDM4E | |
| SCHEMBL26248945 | 0.80 | MAOA (0.52) | CYP1A1CYP1A2CYP2D6CYP1B1PKM | |
| SCHEMBL25753656 | 0.80 | KDM4E (0.51) | PKMKDM4EMAPTNPC1RAB9A | |
| SCHEMBL25753449 | 0.79 | MAPT (0.57) | CYP1A2CYP3A4CYP2D6CYP1B1NQO2 | |
| SCHEMBL25753450 | 0.78 | F3 (0.57) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL25753466 | 0.77 | MAPT (0.55) | CYP3A4CYP1B1NQO2PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230277508-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | Shanghai Ling Xi Biotechnology Development Co., Ltd. (CN) | 2023-09-07 | — | — | US | disclosed |
| US-20230277508-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | Shanghai Ling Xi Biotechnology Development Co., Ltd. (CN) | 2023-09-07 | — | — | US | disclosed |
| EP-4205741-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | Shanghai Ling Xi Biotechnology Development Co., Ltd. (CN) | 2023-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230277508-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | CYP2E1, CYP11B1, CYP27A1 | PTGS2 90/4885CYP1A1 33/4885CYP1A2 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.