Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431130 | 0.85 | NSD2 (0.62) | NSD2SMN1; SMN2PABPC1EIF4HMEN1 | |
| SCHEMBL24059139 | 0.83 | NSD2 (0.67) | NSD2PABPC1EIF4HMEN1KMT2A | |
| SCHEMBL16886350 | 0.80 | NSD2 (0.51) | NSD2SMN1; SMN2PABPC1EIF4HMEN1 | |
| SCHEMBL16572948 | 0.80 | NSD2 (0.67) | NSD2SMN1; SMN2PABPC1EIF4HMEN1 | |
| SCHEMBL25767507 | 0.79 | NSD2 (0.58) | NSD2SMN1; SMN2PABPC1EIF4HMEN1 | |
| SCHEMBL27062558 | 0.79 | NSD2 (0.58) | NSD2SMN1; SMN2PABPC1EIF4HMEN1 | |
| SCHEMBL16294300 | 0.78 | NSD2 (0.57) | NSD2SMN1; SMN2PABPC1EIF4HMEN1 | |
| SCHEMBL268817 | 0.78 | P2RX7 (0.65) | SMN1; SMN2MEN1KMT2AKDM4EPOLB | |
| SCHEMBL163050 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2AKDM4EPOLB | |
| SCHEMBL827107 | 0.77 | MEN1 (0.58) | NSD2SMN1; SMN2PABPC1EIF4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, ALKBH1 | NSD2 1735/4885SMN1; SMN2 285/4885PABPC1 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.