Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 5/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25622879 | 1.00 | L3MBTL1 (0.37) | L3MBTL1WDR5TNFMAPTALDH1A1 | |
| SCHEMBL24036777 | 1.00 | L3MBTL1 (0.37) | L3MBTL1WDR5TNFMAPTALDH1A1 | |
| SCHEMBL25753616 | 0.93 | WDR5 (0.32) | L3MBTL1WDR5TNFMAPTALDH1A1 | |
| SCHEMBL24036879 | 0.93 | WDR5 (0.32) | L3MBTL1WDR5TNFMAPTALDH1A1 | |
| SCHEMBL30389268 | 0.92 | MEN1 (0.32) | L3MBTL1WDR5TNFMEN1KMT2A | |
| SCHEMBL25753606 | 0.92 | MEN1 (0.32) | L3MBTL1WDR5TNFMEN1KMT2A | |
| SCHEMBL25752822 | 0.92 | MEN1 (0.32) | L3MBTL1WDR5TNFMEN1KMT2A | |
| SCHEMBL30388831 | 0.90 | SLC13A3 (0.35) | WDR5MAPTGRNSORT1MAPK1 | |
| SCHEMBL25752815 | 0.90 | SLC13A3 (0.35) | WDR5MAPTGRNSORT1MAPK1 | |
| SCHEMBL25753540 | 0.90 | SLC13A3 (0.35) | WDR5MAPTGRNSORT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | L3MBTL1 2036/4885WDR5 2145/4885TNF 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.