Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.33 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25623203 | 1.00 | DDR1 (0.36) | DDR1CTSAITGB1HDAC3HDAC1 | |
| SCHEMBL24036777 | 0.89 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1WDR5GAAMAPT | |
| SCHEMBL25622879 | 0.89 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1WDR5GAAMAPT | |
| SCHEMBL25753602 | 0.89 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1WDR5GAAMAPT | |
| SCHEMBL25753629 | 0.88 | MEN1 (0.32) | ITGB1ITGA4WDR5MAPT | |
| SCHEMBL25623014 | 0.88 | MEN1 (0.32) | ITGB1ITGA4WDR5MAPT | |
| SCHEMBL24036896 | 0.88 | MEN1 (0.32) | ITGB1ITGA4WDR5MAPT | |
| SCHEMBL24036539 | 0.87 | HTR2C (0.34) | DDR1ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL25753649 | 0.87 | HTR2C (0.34) | DDR1ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL30388831 | 0.86 | SLC13A3 (0.35) | DDR1CTSARAPGEF3WDR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | DDR1 4295/4885CTSA 4587/4885ITGB1 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.