Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753887 | 0.95 | HDAC2 (0.49) | ALDH1A1HTTKDM4EGAACNR2 | |
| SCHEMBL25753957 | 0.85 | KDM4E (0.46) | ALDH1A1HTTKDM4EHDAC2HDAC6 | |
| SCHEMBL21939844 | 0.85 | F13A1 (0.51) | ALDH1A1HDAC2HDAC6F13A1MAPT | |
| SCHEMBL21940137 | 0.84 | HDAC2 (0.51) | ALDH1A1HTTKDM4EHDAC2HDAC6 | |
| SCHEMBL4451690 | 0.84 | HDAC2 (0.48) | ALDH1A1HTTKDM4EHDAC2HDAC6 | |
| SCHEMBL21939615 | 0.83 | F13A1 (0.49) | ALDH1A1HDAC2HDAC6F13A1HDAC3 | |
| SCHEMBL21878889 | 0.81 | MAPT (0.59) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL25753950 | 0.80 | PTPRC (0.47) | ALDH1A1HTTKDM4EGAAHDAC2 | |
| SCHEMBL9709635 | 0.80 | MAPT (0.54) | ALDH1A1HTTKDM4EHDAC2HDAC6 | |
| SCHEMBL30201802 | 0.80 | MAPT (0.54) | ALDH1A1HTTKDM4EHDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-B1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV TASMANIA (AU) | 2023-06-21 | — | — | EP | disclosed |