Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939833 | 0.95 | PTPRC (0.49) | PTPRCMAPTPGRHTR1AADORA3 | |
| SCHEMBL25753851 | 0.85 | RECQL (0.49) | PTPRCGAAPTPN13MAPTKDM4E | |
| SCHEMBL25753957 | 0.85 | KDM4E (0.46) | PTPRCPTPN13MAPTKDM4EAPAF1 | |
| SCHEMBL25753979 | 0.80 | ALDH1A1 (0.47) | GAAMAPTPGRMAPK1PDE3A | |
| SCHEMBL25753852 | 0.80 | LMNA (0.48) | PTPRCPTPN13MAPTPGRHTR1A | |
| SCHEMBL21939609 | 0.79 | HDAC1 (0.48) | MAPTTDP1HDAC2HDAC6HDAC8 | |
| SCHEMBL13814546 | 0.78 | MALT1 (0.55) | GAAMAPTKDM4EAPAF1MITF | |
| SCHEMBL21939938 | 0.77 | ACE (0.48) | MAPTTDP1HDAC6HDAC1 | |
| SCHEMBL25754017 | 0.76 | PTPRC (0.48) | PTPRCPTPN13LMNAL3MBTL1TLR2 | |
| SCHEMBL21939844 | 0.76 | F13A1 (0.51) | MAPTALDH1A1HDAC2HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-B1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV TASMANIA (AU) | 2023-06-21 | — | — | EP | disclosed |