Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753979 | 0.95 | ALDH1A1 (0.47) | HDAC2HDAC6LMNAALDH1A1HTT | |
| SCHEMBL21940137 | 0.88 | HDAC2 (0.51) | HDAC2HDAC6LMNAPKMALDH1A1 | |
| SCHEMBL4451690 | 0.88 | HDAC2 (0.48) | HDAC2HDAC6LMNAPKMALDH1A1 | |
| SCHEMBL25753852 | 0.84 | LMNA (0.48) | HDAC2HDAC6LMNAPKMALDH1A1 | |
| SCHEMBL21878898 | 0.84 | TRPV1 (0.50) | HDAC2HDAC6LMNAPKMALDH1A1 | |
| SCHEMBL1783475 | 0.83 | CNR1 (0.40) | LMNAALDH1A1HTTMAPTTDP1 | |
| SCHEMBL25753851 | 0.82 | RECQL (0.49) | HDAC2HDAC6LMNAPKMALDH1A1 | |
| SCHEMBL21939615 | 0.81 | F13A1 (0.49) | HDAC2HDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL21939844 | 0.80 | F13A1 (0.51) | HDAC2HDAC6ALDH1A1MAPTNPC1 | |
| SCHEMBL13649358 | 0.80 | MAPT (0.53) | LMNAPKMALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-B1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV TASMANIA (AU) | 2023-06-21 | — | — | EP | disclosed |