Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753852 | 0.95 | LMNA (0.48) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL29263294 | 0.85 | MAPT (0.54) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL9709635 | 0.85 | MAPT (0.54) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL30201802 | 0.85 | MAPT (0.54) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL21940525 | 0.85 | MAPT (0.54) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL25753979 | 0.85 | ALDH1A1 (0.47) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL25753950 | 0.85 | PTPRC (0.47) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL11421782 | 0.84 | MAPT (0.55) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL25753851 | 0.82 | RECQL (0.49) | KDM4EAPAF1MITFALDH1A1LMNA | |
| SCHEMBL21939844 | 0.80 | F13A1 (0.51) | ALDH1A1MAPTHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-B1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV TASMANIA (AU) | 2023-06-21 | — | — | EP | disclosed |