Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 11/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355303 | 0.83 | CA2 (0.55) | CA2KMT2AKDM4ECA1CA9 | |
| SCHEMBL25753420 | 0.79 | CA2 (0.66) | CA2KMT2AKDM4ECA1CA9 | |
| SCHEMBL3359455 | 0.77 | CA2 (0.55) | CA2KMT2AKDM4ECA1CA9 | |
| SCHEMBL27794162 | 0.77 | CA2 (0.60) | CA2KMT2AKDM4ECA1CA9 | |
| SCHEMBL19271911 | 0.75 | NAAA (0.56) | NPSR1GAA | |
| SCHEMBL15906767 | 0.74 | CA2 (1.00) | CA2KMT2AKDM4ECA1CA9 | |
| SCHEMBL21137664 | 0.73 | HDAC1 (0.43) | KMT2AMEN1LMNAHTT | |
| SCHEMBL7122102 | 0.73 | KMT2A (1.00) | CA2KMT2AKDM4ECA1CA9 | |
| SCHEMBL22832224 | 0.72 | POLB (0.50) | NPSR1 | |
| SCHEMBL22832225 | 0.72 | POLB (0.50) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |