Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27062442 | 0.77 | GAA (0.42) | KMT2ALMNA | |
| SCHEMBL20307128 | 0.75 | KMT2A (0.35) | KMT2AEPHX2LMNA | |
| SCHEMBL25754079 | 0.72 | SMN1; SMN2 (0.50) | KMT2AHRH2HRH1EPHX2 | |
| SCHEMBL25129052 | 0.68 | HSD17B10 (0.54) | HRH2HRH1 | |
| SCHEMBL11985627 | 0.68 | LMNA (0.39) | KMT2ALMNA | |
| SCHEMBL16207590 | 0.67 | HTT (0.49) | KMT2AEPHX2LMNA | |
| SCHEMBL21761115 | 0.65 | L3MBTL1 (0.44) | KMT2A | |
| SCHEMBL3986821 | 0.64 | CYP3A4 (0.57) | KMT2A | |
| SCHEMBL21017438 | 0.62 | ALDH1A1 (0.39) | LMNA | |
| SCHEMBL21811196 | 0.62 | CYP3A4 (0.42) | KMT2AHRH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |