Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754230 | 0.89 | USP2 (0.44) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL25754247 | 0.87 | USP2 (0.51) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL25754243 | 0.87 | USP2 (0.51) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL25754231 | 0.87 | USP2 (0.55) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL25754242 | 0.81 | USP2 (0.49) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL25754236 | 0.81 | HTT (0.33) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6466390 | 0.81 | SPHK1 (0.50) | HTTMAPTSPHK1CYP1A2CYP3A4 | |
| SCHEMBL8836714 | 0.81 | SPHK1 (0.50) | HTTMAPTSPHK1CYP1A2CYP3A4 | |
| SCHEMBL28339798 | 0.81 | SPHK1 (0.50) | HTTMAPTSPHK1CYP1A2CYP3A4 | |
| SCHEMBL10617834 | 0.81 | SPHK1 (0.50) | HTTMAPTSPHK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | HTT 916/4885MEN1 940/4885THRB 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.