Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754243 | 0.96 | USP2 (0.51) | USP2HTTSPHK1LPAR5LPAR1 | |
| SCHEMBL25754247 | 0.96 | USP2 (0.51) | USP2HTTSPHK1LPAR5LPAR1 | |
| SCHEMBL25754242 | 0.91 | USP2 (0.49) | USP2HTTSPHK1LPAR5LPAR1 | |
| SCHEMBL25754224 | 0.87 | HTT (0.48) | USP2HTTSPHK1LPAR5LPAR1 | |
| SCHEMBL25754237 | 0.82 | HTT (0.42) | USP2HTTSPHK1LPAR5PLA2G2C | |
| SCHEMBL25754235 | 0.82 | HTT (0.42) | USP2HTTSPHK1LPAR5CYP3A4 | |
| SCHEMBL25754239 | 0.81 | HTT (0.41) | USP2HTTSPHK1LPAR5CYP3A4 | |
| SCHEMBL25754240 | 0.81 | HTT (0.41) | USP2HTTSPHK1LPAR5MEN1 | |
| SCHEMBL25754230 | 0.80 | USP2 (0.44) | USP2HTTSPHK1LPAR5MEN1 | |
| SCHEMBL29169783 | 0.80 | SPHK1 (0.69) | USP2HTTSPHK1LPAR5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | USP2 51/4885HTT 916/4885SPHK1 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.