⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754332 | 0.94 | HDAC6 (0.32) | — | |
| SCHEMBL25754329 | 0.89 | PAOX (0.38) | — | |
| SCHEMBL25754211 | 0.83 | CES2 (0.38) | — | |
| SCHEMBL25754318 | 0.83 | HDAC6 (0.41) | — | |
| SCHEMBL25754338 | 0.80 | CYP1A2 (0.34) | — | |
| SCHEMBL25754209 | 0.77 | CES2 (0.38) | — | |
| SCHEMBL25754215 | 0.75 | CES2 (0.37) | — | |
| SCHEMBL25754217 | 0.75 | CES2 (0.37) | — | |
| SCHEMBL25754330 | 0.75 | MAOA (0.34) | — | |
| SCHEMBL25754333 | 0.74 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |