SCHEMBL25754318

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25754329	0.91	PAOX (0.38)	HDAC6PAOXCASP2CA12F13A1
	SCHEMBL25754332	0.90	HDAC6 (0.32)	HDAC6PAOXMEN1KMT2ASMN1; SMN2
	SCHEMBL25754333	0.86	KDM4E (0.42)	MEN1KMT2AHSD17B10TSHRSMN1; SMN2
	SCHEMBL25754320	0.83	—	—
	SCHEMBL25754209	0.82	CES2 (0.38)	PAOX
	SCHEMBL25754338	0.82	CYP1A2 (0.34)	CYP1A2MEN1CYP2C19RECQLKMT2A
	SCHEMBL25754343	0.81	SAT1 (0.37)	CYP1A2MEN1CYP2C19RECQLKMT2A
	SCHEMBL25754217	0.81	CES2 (0.37)	PAOXALOX15MEN1RECQLKMT2A
	SCHEMBL25754215	0.81	CES2 (0.37)	PAOXALOX15MEN1RECQLKMT2A
	SCHEMBL25754211	0.79	CES2 (0.38)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.