Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754580 | 1.00 | HRH3 (0.48) | HRH3MAPTKCNH2HRH4 | |
| SCHEMBL25754588 | 0.94 | HRH3 (0.44) | HRH3MAPTKCNH2 | |
| SCHEMBL25754576 | 0.94 | HRH3 (0.48) | HRH3MAPTKCNH2HRH4 | |
| SCHEMBL25754584 | 0.94 | HRH3 (0.48) | HRH3MAPTKCNH2HRH4 | |
| SCHEMBL25754581 | 0.94 | HRH3 (0.44) | HRH3MAPTKCNH2 | |
| SCHEMBL25754568 | 0.93 | HRH3 (0.43) | HRH3MAPTKCNH2 | |
| SCHEMBL25754570 | 0.86 | HRH3 (0.60) | HRH3MAPT | |
| SCHEMBL25754692 | 0.84 | SIGMAR1 (0.38) | HRH3KCNH2 | |
| SCHEMBL25754675 | 0.83 | SIGMAR1 (0.37) | HRH3KCNH2 | |
| SCHEMBL25754677 | 0.82 | HRH3 (0.38) | HRH3MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | HRH3 1596/4885MAPT 1198/4885KCNH2 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.