Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754601 | 0.77 | ALDH1A1 (0.42) | USP2HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL24059282 | 0.68 | ALDH1A1 (0.46) | USP2HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL13260709 | 0.66 | — | — | |
| SCHEMBL21564774 | 0.65 | USP2 (0.50) | USP2HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL25798184 | 0.65 | CYP1A2 (0.34) | HSD17B10ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL25767748 | 0.65 | ALDH1A1 (0.43) | USP2HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL14611505 | 0.64 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL18938259 | 0.64 | CA1 (0.35) | — | |
| SCHEMBL11433586 | 0.64 | SIGMAR1 (0.36) | USP2HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL19954172 | 0.63 | CYP1A2 (0.41) | ADH1AADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |