SCHEMBL25754618

SCHEMBL25754618

CC#C[C@@H]1C[C@@H](N2CCCCC2)CN1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.36
HTR6 P50406 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754629 0.71 DPP4 (0.34) DPP4
SCHEMBL16015163 0.69 DPP4 (0.39) DPP4HTR6
SCHEMBL10905245 0.62 DPP4 (0.61) DPP4
SCHEMBL24700271 0.62 HTR6 (0.44) DPP4HTR6
Hydrochloric Acid SCHEMBL17843428 0.61 DPP4 (0.60) DPP4
Hydrochloric Acid SCHEMBL19744597 0.61 DPP4 (0.60) DPP4
Hydrochloric Acid SCHEMBL19746027 0.61 DPP4 (0.60) DPP4
Hydrochloric Acid SCHEMBL23124068 0.60 HTR6 (0.42) DPP4HTR6
SCHEMBL2475741 0.60 HTR6 (0.56) DPP4HTR6
SCHEMBL3278728 0.60 HTR6 (0.56) DPP4HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 DPP4 1068/4885HTR6 3748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.