⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754643 | 0.74 | SIGMAR1 (0.37) | — | |
| SCHEMBL25754645 | 0.66 | HRH3 (0.40) | — | |
| SCHEMBL27046713 | 0.65 | GNAI3 (0.35) | — | |
| SCHEMBL25754634 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL3262585 | 0.62 | OPRM1 (0.40) | — | |
| SCHEMBL222504 | 0.61 | KDM1A (0.34) | — | |
| SCHEMBL3264745 | 0.60 | KMT2A (0.46) | — | |
| SCHEMBL3418583 | 0.60 | PIK3CD (0.44) | — | |
| Hydrochloric Acid SCHEMBL3264620 | 0.59 | GNAI3 (0.47) | — | |
| Hydrochloric Acid SCHEMBL3368698 | 0.59 | GNAI3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |