Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442819 | 0.83 | ENPEP (0.41) | FOLH1 | |
| SCHEMBL3657980 | 0.83 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL3794716 | 0.80 | FOLH1 (0.33) | FOLH1 | |
| SCHEMBL28549775 | 0.77 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL3627637 | 0.77 | SPHK1 (0.38) | — | |
| SCHEMBL28101183 | 0.76 | LMNA (0.39) | FOLH1 | |
| SCHEMBL4620815 | 0.76 | ENPEP (0.36) | FOLH1 | |
| SCHEMBL25906028 | 0.75 | MME (0.31) | — | |
| SCHEMBL7075113 | 0.75 | LMNA (0.35) | — | |
| SCHEMBL3020499 | 0.75 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382199-B1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | GFBIOCHEMICALS LTD (MT) | 2016-11-16 | — | — | EP | disclosed |
| US-20150175568-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | GFBIOCHEMICALS LIMITED (MT) | 2015-06-25 | — | — | US | disclosed |
| US-8969559-B2 | Ketal amide compounds, methods of making, and applications | SEGETIS, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130053564-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | SEGETIS, INC. (US) | 2013-02-28 | — | — | US | disclosed |
| EP-2382199-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | Segetis, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010075330-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | SEGETIS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| EP-0359464-B1 | Heat resistant polyvinyl chloride copolymer and preparation process of the copolymer | MITSUI TOATSU CHEMICALS (JP) | 1994-07-20 | — | — | EP | disclosed |
| EP-0359464-A2 | Heat resistant polyvinyl chloride copolymer and preparation process of the copolymer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053564-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | KAT6A, KAT6B, KAT5 | FOLH1 2410/4885 |
| US-20150175568-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | KAT6A, KAT6B, KAT5 | FOLH1 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.