Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563050 | 0.78 | P2RX7 (0.51) | P2RX7P2RY12TYK2HPGDKMT2A | |
| SCHEMBL31104526 | 0.73 | P2RX7 (0.56) | P2RX7P2RY12TYK2HPGDALDH1A1 | |
| SCHEMBL7984549 | 0.72 | TYK2 (0.62) | P2RX7P2RY12TYK2HPGDKMT2A | |
| SCHEMBL14160488 | 0.70 | P2RX7 (0.55) | P2RX7P2RY12TYK2HPGDKMT2A | |
| SCHEMBL9519109 | 0.70 | NLRP3 (0.67) | KMT2AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL21668146 | 0.70 | TYK2 (0.51) | P2RX7P2RY12TYK2KMT2AALDH1A1 | |
| SCHEMBL30513967 | 0.70 | TYK2 (0.51) | P2RX7P2RY12TYK2KMT2AALDH1A1 | |
| SCHEMBL14160433 | 0.69 | P2RX7 (0.64) | P2RX7P2RY12TYK2HPGDKMT2A | |
| SCHEMBL1180024 | 0.69 | KDM4E (0.60) | P2RX7P2RY12TYK2KMT2AALDH1A1 | |
| SCHEMBL7871675 | 0.68 | LMNA (0.52) | P2RX7P2RY12KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399416-B1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-11-02 | — | — | EP | disclosed |