SCHEMBL25754776

SCHEMBL25754776

CC#CCCCCCCCCCn1ccnn1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.33
TBXAS1 P24557 2/20 0.32
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754786 0.88 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3
SCHEMBL25754781 0.88 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL25754778 0.85 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL25755002 0.85
SCHEMBL25754780 0.85 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3
SCHEMBL25754784 0.85 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3
SCHEMBL3302887 0.76 TBXAS1 (0.46) CYP19A1TBXAS1
SCHEMBL245885 0.76 TBXAS1 (0.46) CYP19A1TBXAS1
SCHEMBL243704 0.76 TBXAS1 (0.46) CYP19A1TBXAS1
SCHEMBL21925549 0.76 TBXAS1 (0.46) CYP19A1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 CYP19A1 2065/4885TBXAS1 3771/4885SLC6A2 4723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.