SCHEMBL25754800

SCHEMBL25754800

CC#CC(O)CCCCCCCCn1ccnn1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.32
CYP19A1 P11511 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31
APH1A Q96BI3 1/20 0.31
PSENEN Q9NZ42 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754807 0.88 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3
SCHEMBL25754804 0.88 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL25754801 0.87 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL25754802 0.82 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL25754805 0.82 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL25755023 0.82
SCHEMBL25755045 0.76
SCHEMBL13223892 0.74 DPP4 (0.38) DPP4CYP19A1SLC6A2SLC6A4SLC6A3
SCHEMBL243704 0.73 TBXAS1 (0.46) CYP19A1
SCHEMBL3302887 0.73 TBXAS1 (0.46) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 DPP4 1068/4885CYP19A1 2065/4885SLC6A2 4723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.