Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199471 | 0.83 | GPR35 (0.31) | — | |
| SCHEMBL22729431 | 0.70 | GPR35 (0.39) | ERCC5FEN1BRD4 | |
| SCHEMBL13377367 | 0.68 | BRD4 (0.35) | ERCC5FEN1BRD4PDPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27199558 | 0.68 | AURKA (0.34) | ERCC5FEN1BRD4 | |
| SCHEMBL22729423 | 0.66 | KDM4E (0.38) | — | |
| SCHEMBL22729400 | 0.66 | BCAT2 (0.38) | ERCC5FEN1BRD4 | |
| SCHEMBL27199691 | 0.65 | BCAT2 (0.35) | ERCC5FEN1BRD4 | |
| SCHEMBL13833648 | 0.64 | ERCC5 (0.40) | ERCC5FEN1ADORA2BBRD4 | |
| SCHEMBL13833647 | 0.63 | LMNA (0.49) | ERCC5FEN1SMN1; SMN2 | |
| SCHEMBL24322161 | 0.62 | ERCC5 (0.36) | ERCC5FEN1ADORA2BPDPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |