SCHEMBL25755150

SCHEMBL25755150

CNC(=O)CNCCCCOCCc1c[nH]nn1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LTA4H P09960 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25755163 0.96 KDM4E (0.34) KDM4EALDH1A1GAA
SCHEMBL25755147 0.91 KDM4E (0.34) KDM4EALDH1A1GAA
SCHEMBL25755159 0.89
SCHEMBL25755165 0.87 CYP3A4 (0.34) GAA
SCHEMBL25755154 0.85 LTA4H (0.31) LTA4H
SCHEMBL25754859 0.84 GAA (0.36) GAA
SCHEMBL25755143 0.83 CYP2C19 (0.30)
SCHEMBL25755205 0.82
SCHEMBL25755302 0.82 LTA4H (0.33) KDM4EALDH1A1LTA4HGAA
SCHEMBL25754858 0.80 GAA (0.34) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 KDM4E 2658/4885ALDH1A1 2539/4885LTA4H 979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.