SCHEMBL25755500

SCHEMBL25755500

C=C(C)C(=O)OCC1CCC(C)O1

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
TSHR P16473 4/20 0.42
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
THRB P10828 1/20 0.36
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577034 0.90 ALDH1A1 (0.70) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19
SCHEMBL25755497 0.83 ALDH1A1 (0.41) ALDH1A1CYP3A4TP53
SCHEMBL241719 0.83 ALDH1A1 (0.66) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19
SCHEMBL16197759 0.82 PDK1 (0.39) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19
SCHEMBL31184251 0.81 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19
SCHEMBL16076546 0.81 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19
SCHEMBL19050235 0.80 TSHR (0.47) ALDH1A1TSHRTHRB
Propylene Oxide SCHEMBL16949951 0.79 ALDH1A1 (0.89) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19
SCHEMBL244871 0.77 ALDH1A1 (0.73) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19
SCHEMBL5098171 0.77 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174734-A1 THERMALLY EXPANDABLE MICROSPHERES PREPARED FROM BIO-BASED MONOMERS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-06-08 US disclosed