SCHEMBL25756042

SCHEMBL25756042

CC(C)(C)OC(=O)N(CCCCCCCCCC(=O)O)[C@H]1CC[C@@H](N=[N+]=[N-])CC1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
KDM5A P29375 4/20 0.32
PHF8 Q9UPP1 4/20 0.32
KDM2A Q9Y2K7 4/20 0.32
KDM4C Q9H3R0 3/20 0.32
KDM7A Q6ZMT4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KDM4A O75164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25031556 1.00 HDAC1 (0.32) HDAC1HDAC2HDAC6KDM5APHF8
SCHEMBL25755991 1.00 HDAC1 (0.32) HDAC1HDAC2HDAC6KDM5APHF8
SCHEMBL25031758 0.91 HDAC1 (0.32) HDAC1HDAC2HDAC6
SCHEMBL25756043 0.89 HDAC1 (0.31) HDAC1HDAC2HDAC6KDM5A
SCHEMBL25773087 0.89
SCHEMBL25756091 0.89
SCHEMBL25031557 0.87 USP2 (0.34) HDAC1HDAC2HDAC6ALDH1A1
SCHEMBL25755995 0.87 USP2 (0.34) HDAC1HDAC2HDAC6ALDH1A1
SCHEMBL25771561 0.87 L3MBTL1 (0.33) L3MBTL1
SCHEMBL25755938 0.87 L3MBTL1 (0.33) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 HDAC1 596/4885HDAC2 1263/4885HDAC6 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.