SCHEMBL25756491

SCHEMBL25756491

C#CCCOCCCCO

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 3/20 0.36
MAPK1 P28482 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25755650 0.93
SCHEMBL18537901 0.87 CA2 (0.39) TSHRCA2CA9
SCHEMBL15803977 0.85 CA2 (0.37) MEN1KMT2ATHRBHTTMAPT
SCHEMBL23015001 0.84 MAPT (0.40) GAAMEN1KMT2ATHRBHTT
SCHEMBL25755556 0.83 TSHR (0.37) GAAMEN1KMT2ATHRBHTT
SCHEMBL16561495 0.82
SCHEMBL31173813 0.81 TSHR (0.48) GAAMEN1KMT2ATHRBHTT
SCHEMBL31225624 0.80 MEN1 (0.58) MEN1KMT2ATHRBHTTMAPT
SCHEMBL6550892 0.80 MEN1 (0.34) MEN1KMT2ATHRBHTTMAPT
SCHEMBL13627808 0.79 MEN1 (0.50) MEN1KMT2ATHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 GAA 520/4885MEN1 940/4885KMT2A 1974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.