SCHEMBL257566

SCHEMBL257566

Nn1c2ccccc2c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.52
CYP1A2 P05177 3/20 0.50
CYP2C19 P33261 2/20 0.50
KDM4E B2RXH2 4/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MEN1 O00255 6/20 0.43
KMT2A Q03164 6/20 0.43
MAPT P10636 5/20 0.43
GAA P10253 1/20 0.43
POLB P06746 2/20 0.42
CYP19A1 P11511 1/20 0.42
BACE1 P56817 2/20 0.41
NOS2 P35228 1/20 0.41
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17689971 0.89 GPR3 (0.44) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL13060362 0.84 ALDH1A1 (0.54) CYP2C19KDM4EATML3MBTL1MEN1
SCHEMBL18388999 0.84 GPR3 (0.39) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL18389063 0.84 GPR3 (0.44) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL31135510 0.82 ALDH1A1 (0.62) GPR3CYP1A2CYP2C19KDM4EL3MBTL1
SCHEMBL19006623 0.82 ALDH1A1 (0.38) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL20651336 0.82 ALDH1A1 (0.49) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL22780595 0.82 ALDH1A1 (0.62) GPR3CYP1A2CYP2C19KDM4EL3MBTL1
SCHEMBL25058983 0.80 ATM (0.50) GPR3CYP1A2CYP2C19KDM4EATM
SCHEMBL257563 0.80 MAOA (0.46) GPR3CYP1A2CYP2C19KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-108530465-B Visible light sensitive information recording material and preparation method thereof 北京化工大学 2020-06-05 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
CN-100368399-C N-bromo carbazole, and its preparing method UNIV SHANXI (CN) 2008-02-13 CN claimed
CN-1850800-A N-bromo carbazole, and its preparing method UNIV SHANXI (CN) 2006-10-25 CN claimed
JP-1157922-A None JP disclosed
CN-120136928-A Organic electroluminescent material and device 环球展览公司 2025-06-13 CN disclosed
CN-118993984-A Synthesis method of N-amido carbazole compound 广东石油化工学院 2024-11-22 CN disclosed
CN-113429559-B Six-arm polyethylene glycol derivative with terminal iso-functionalization and preparation method thereof 厦门赛诺邦格生物科技股份有限公司 2024-08-23 CN disclosed
EP-3416948-B1 INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS UNIV QUEENSLAND (AU) 2024-07-24 EP disclosed
EP-3790875-B1 N-HETEROARYLENE COMPOUNDS WITH LOW LUMO ENERGIES NOVALED GMBH (DE) 2024-07-03 EP disclosed
EP-4395521-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE COMPRISING THE CONDENSED CYCLIC COMPOUND, AND ELECTRONIC APPARATUS COMPRISING THE LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
US-4246422-A Naphtholactam dyestuffs CIBA-GEIGY AG (CH) 1981-01-20 US disclosed
US-4246410-A BENZINDOLE DYES OF YELLOW AND RED CIBA -GEIGY AKTIENGESELLSCHAFT (CH) 1981-01-20 US disclosed
US-4236007-A YELLOW SHADES ON POLYESTERS CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-25 US disclosed
US-4180665-A Substituted 3-benz(cd)indol-2-(1H)-ylidene-furo[2,3-b]quinoxalin-2(3H)one dyestuffs CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1979-12-25 US disclosed
US-4159379-A Dispersion dyestuffs of the naphtholactam series CIBA-GEIGY AG (CH) 1979-06-26 US disclosed
US-4148805-A POLYESTERS, RED, YELLLOW CIBA-GEIGY AG (CH) 1979-04-10 US disclosed
US-4146541-A YELLOW SHADE ON POLYESTERS CIBA-GEIGY AG (CH) 1979-03-27 US disclosed
US-3981869-A BENZOTHIAZOLE, BENZOXAZOLE AND INDOLE DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US disclosed