Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757056 | 0.91 | AURKA (0.32) | CNR1AURKASYKAURKBMEN1 | |
| SCHEMBL25756719 | 0.83 | PDE5A (0.36) | LMNAHTTTSHRCNR1KDM4E | |
| SCHEMBL27199496 | 0.82 | CNR1 (0.35) | LMNAHTTTSHRCNR1KDM4E | |
| SCHEMBL27199522 | 0.76 | TRPA1 (0.33) | LMNAMAPTAURKASYKAURKB | |
| SCHEMBL25752395 | 0.73 | CNR1 (0.33) | LMNAHTTTSHRCNR1KDM4E | |
| SCHEMBL25757055 | 0.72 | OPRM1 (0.34) | AURKASYKAURKB | |
| Hydrochloric Acid SCHEMBL27199341 | 0.72 | CNR1 (0.32) | LMNAHTTTSHRCNR1KDM4E | |
| SCHEMBL25757053 | 0.72 | CNR1 (0.34) | LMNAHTTTSHRCNR1KDM4E | |
| SCHEMBL25750536 | 0.71 | SCN9A (0.41) | CNR1 | |
| SCHEMBL25750514 | 0.70 | SCN9A (0.34) | LMNAHTTTSHRCNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |