Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756718 | 0.91 | LMNA (0.32) | AURKASYKAURKBMEN1KMT2A | |
| SCHEMBL27199522 | 0.85 | TRPA1 (0.33) | AURKASYKAURKBMEN1KMT2A | |
| SCHEMBL25752395 | 0.82 | CNR1 (0.33) | MEN1KMT2ACNR1 | |
| SCHEMBL25757053 | 0.81 | CNR1 (0.34) | MEN1KMT2ACNR1 | |
| Hydrochloric Acid SCHEMBL27199341 | 0.81 | CNR1 (0.32) | MEN1KMT2ACNR1 | |
| SCHEMBL25757055 | 0.80 | OPRM1 (0.34) | AURKASYKAURKB | |
| SCHEMBL25756719 | 0.72 | PDE5A (0.36) | MEN1KMT2ACNR1 | |
| SCHEMBL27199496 | 0.72 | CNR1 (0.35) | MEN1KMT2ACNR1 | |
| SCHEMBL30498126 | 0.71 | TYK2 (0.33) | — | |
| SCHEMBL25750514 | 0.69 | SCN9A (0.34) | AURKASYKAURKBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |