SCHEMBL2575829

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14479018	0.97	FFAR1 (0.43)	FFAR4FFAR1PRKAB2PRKAG1PRKAA2
	SCHEMBL2588182	0.90	FFAR4 (0.52)	FFAR4FFAR1METKDR
	SCHEMBL1136103	0.90	MET (0.40)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
	SCHEMBL2493104	0.90	MET (0.41)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
	SCHEMBL2584922	0.89	PTGDR2 (0.50)	FFAR1PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL2463861	0.89	PTPN1 (0.41)	FFAR4FFAR1METAXLKDR
	SCHEMBL1136262	0.86	MET (0.43)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
	SCHEMBL1136119	0.86	MAOB (0.40)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
	SCHEMBL1136175	0.85	MTNR1B (0.45)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
	SCHEMBL2578819	0.85	PDE4A (0.42)	METKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.