Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704493 | 0.76 | CYP1A2 (0.36) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL130702 | 0.72 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL130407 | 0.72 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL4409891 | 0.71 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL130521 | 0.69 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL130798 | 0.69 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29685062 | 0.69 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL21282826 | 0.67 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL26973527 | 0.67 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29385938 | 0.67 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177808-A1 | MODIFIED GAPMER OLIGOMERS AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023122316-A2 | SPLICE SWITCH OLIGONUCLEOTIDE (SSO) MOLECULES FOR TARGETING β-CATENIN AND USES THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | WO | disclosed |