Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556564 | 0.91 | HSD17B1 (0.40) | HSD17B1HSD17B2HTTSMN1; SMN2PIM1 | |
| SCHEMBL14488203 | 0.90 | HSD17B1 (0.42) | HSD17B1HSD17B2HTTSMN1; SMN2PTK2B | |
| SCHEMBL250118 | 0.90 | PTK2B (0.45) | HSD17B1HSD17B2SMN1; SMN2PTK2BLMNA | |
| SCHEMBL14547178 | 0.88 | PTK2B (0.44) | HSD17B1HSD17B2SMN1; SMN2PTK2BTDP1 | |
| SCHEMBL1682113 | 0.88 | PTK2B (0.44) | HSD17B1HSD17B2SMN1; SMN2PTK2BLMNA | |
| SCHEMBL2489571 | 0.88 | PTK2B (0.44) | HSD17B1HSD17B2SMN1; SMN2PTK2BLMNA | |
| SCHEMBL1681521 | 0.88 | PTK2B (0.44) | HSD17B1HSD17B2SMN1; SMN2PTK2BLMNA | |
| SCHEMBL2176795 | 0.88 | PTK2B (0.44) | HSD17B1HSD17B2SMN1; SMN2PTK2BLMNA | |
| SCHEMBL4355959 | 0.84 | SMN1; SMN2 (0.53) | HSD17B1HSD17B2HTTSMN1; SMN2PIM1 | |
| SCHEMBL250982 | 0.83 | LTA4H (0.46) | HSD17B1HSD17B2SMN1; SMN2PTK2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230216082-A1 | POLYELECTROLYTE COMPOSITES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-07-06 | — | — | US | disclosed |