Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15964615 | 0.83 | ATM (0.48) | ATMALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL2707447 | 0.80 | RAB9A (0.58) | ALDH1A1RAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL25760467 | 0.75 | SMN1; SMN2 (0.51) | ATMALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18366876 | 0.73 | RIPK1 (0.50) | ATMALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL30434549 | 0.73 | RIPK1 (0.50) | ATMALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL17610948 | 0.71 | P2RY14 (0.48) | ATMALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL15022419 | 0.71 | NOTUM (0.41) | ATMKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9858144 | 0.71 | CA5A (0.55) | ATMALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL10667411 | 0.70 | CA5A (0.53) | ATMALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL17611000 | 0.69 | KMT2A (0.59) | ATMALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119210-A1 | NOVEL COMPOUND AS RIPK1 INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 제일약품주식회사 | 2023-06-29 | — | — | WO | disclosed |