SCHEMBL25759673

SCHEMBL25759673

O=S(=O)(NCCCN1CCC(Cc2ccccc2)CC1)c1cccc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.57
HTR7 P34969 6/20 0.56
CCR1 P32246 1/20 0.56
HTR6 P50406 4/20 0.55
DRD2 P14416 3/20 0.55
HTR2A P28223 3/20 0.55
NPY5R Q15761 1/20 0.54
SLC6A2 P23975 5/20 0.52
SLC6A4 P31645 4/20 0.52
HTR1A P08908 1/20 0.52
SLC6A3 Q01959 2/20 0.51
CCR3 P51677 2/20 0.51
MAPT P10636 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
SCN1A P35498 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24070145 0.94 NPY5R (0.60) DRD4HTR7HTR6DRD2HTR2A
SCHEMBL25759707 0.86 BCHE (0.63) HTR7CCR1HTR6DRD2HTR2A
SCHEMBL24069062 0.84 HTR7 (0.68) HTR7CCR1HTR6DRD2HTR2A
SCHEMBL30376178 0.83 HTR7 (0.69) HTR7SLC6A2SLC6A4SLC6A3CCR3
SCHEMBL11111481 0.83 HTR7 (0.66) HTR7CCR1HTR6DRD2HTR2A
SCHEMBL25289791 0.81 HTR7 (0.73) HTR7CCR1HTR6DRD2HTR2A
SCHEMBL11101165 0.81 HTR7 (0.67) HTR7CCR1HTR6DRD2HTR2A
Hydrochloric Acid SCHEMBL11111993 0.80 HTR7 (0.67) HTR7CCR1HTR6DRD2HTR2A
SCHEMBL24069430 0.79 SLC6A2 (0.57) HTR7SLC6A2SLC6A4SLC6A3CCR3
SCHEMBL24069429 0.79 SLC6A2 (0.63) HTR7SLC6A2SLC6A4SLC6A3CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 CN claimed
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 CN disclosed
EP-4159718-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2023-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 DRD4 21/4885HTR7 79/4885CCR1 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.