SCHEMBL25759682

SCHEMBL25759682

CCCCCC1CC(CCCCC)CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.54
NAMPT P43490 1/20 0.42
GPR119 Q8TDV5 7/20 0.41
PKM P14618 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
FAAH O00519 1/20 0.39
USP2 O75604 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24501242 0.94 NR1H2 (0.53) NR1H2NAMPTGPR119PKMMEN1
SCHEMBL22906686 0.92 NR1H2 (0.51) NR1H2NAMPTGPR119PKMMEN1
SCHEMBL15297794 0.89 NR1H2 (0.54) NR1H2NAMPTGPR119MEN1KMT2A
SCHEMBL18623977 0.88 NR1H2 (0.46) NR1H2NAMPTGPR119PKMMEN1
SCHEMBL17087673 0.88 NR1H2 (0.46) NR1H2NAMPTGPR119PKMMEN1
SCHEMBL18604606 0.88 NR1H2 (0.46) NR1H2NAMPTGPR119PKMMEN1
SCHEMBL18604605 0.88 NR1H2 (0.46) NR1H2NAMPTGPR119PKMMEN1
SCHEMBL25757567 0.88 NR1H2 (0.57) NR1H2NAMPTGPR119MEN1KMT2A
SCHEMBL25757571 0.87 NR1H2 (0.42) NR1H2NAMPTGPR119MEN1KMT2A
SCHEMBL850478 0.85 GPR119 (0.50) NR1H2GPR119PKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP NR1H2 566/4885NAMPT 1873/4885GPR119 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.