Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782808 | 0.87 | ALDH1A1 (0.36) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20100107 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL20100096 | 0.69 | DPP4 (0.35) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22519128 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL18131814 | 0.64 | PTGS1 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24242314 | 0.64 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL21698413 | 0.64 | ALDH1A1 (0.47) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21698367 | 0.63 | PDE10A (0.32) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18131807 | 0.63 | HSD17B10 (0.33) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18131817 | 0.62 | MAPK1 (0.44) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617207-B1 | CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO LTD (JP) | 2023-06-28 | — | — | EP | disclosed |