Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932263 | 0.80 | LMNA (0.48) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL5306707 | 0.80 | CYP2D6 (0.52) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL1955 | 0.80 | ESR1 (0.53) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL29816355 | 0.80 | CYP2D6 (0.52) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL5933696 | 0.78 | LMNA (0.46) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL446690 | 0.78 | CYP2D6 (0.50) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL9389474 | 0.78 | ESR1 (0.52) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL11096012 | 0.78 | LMNA (0.39) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL5062426 | 0.78 | ALDH1A1 (0.56) | CYP2D6LMNAMAPK1SRCCES2 | |
| SCHEMBL6497920 | 0.78 | CYP1A2 (0.46) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108617-A1 | AUTO-TUNING DRUG REGULATOR CONSTRUCTIONS | RETHINK64 BIONETWORKS PBC (US) | 2026-04-23 | — | — | US | disclosed |
| WO-2024155707-A1 | AUTO-TUNING DRUG REGULATOR CONSTRUCTIONS | RETHINK64 BIONETWORKS PBC (US) | 2024-07-25 | — | — | WO | disclosed |
| WO-2024010810-A2 | FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF | CIDARA THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| EP-2751076-A1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | Spirogen Sàrl (CH) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013053872-A1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | SPIROGEN SÀRL (CH) | 2013-04-18 | — | — | WO | disclosed |
| EP-2558445-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PYRROLOBENZODIAZEPINES | Spirogen Sàrl (CH) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011128650-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PYRROLOBENZODIAZEPINES | SPIROGEN LIMITED (GB) | 2011-10-20 | — | — | WO | disclosed |
| US-5561119-A | ANTITUMOR AGENTS | LABORATOIRES HOECHST (FR) | 1996-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260108617-A1 | AUTO-TUNING DRUG REGULATOR CONSTRUCTIONS | TPMT, CYP2D6, ACHE | CYP2D6 2/4885CYP1A2 118/4885PKM 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.