Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466611 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10308490 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10409275 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10951908 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10409229 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL11871015 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL11861591 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL4951271 | 0.76 | — | — | |
| SCHEMBL10409317 | 0.75 | TSHR (0.36) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL4893786 | 0.75 | ALDH1A1 (0.46) | ALDH1A1CHRM5CHRM1CHRM3PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428092-B2 | Process of producing phosphinothricin employing nitrilases | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20170247399-A1 | PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2017-08-31 | — | — | US | disclosed |
| US-9683001-B2 | Process of producing phosphinothricin employing nitrilases | Stragegic Enzyme Applications, Inc. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20150239917-A1 | Process of Producing Phosphinothricin Employing Nitrilases | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2015-08-27 | — | — | US | disclosed |
| US-8981142-B2 | Process of producing phosphinothricin employing nitrilases | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20130204031-A1 | PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2011129820-A1 | PROCESS FOR PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2011-10-20 | — | — | WO | disclosed |
| US-3962378-A | Preparation of phosphorus-organic esters | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247399-A1 | PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES | NPEPPS, NISCH, NAAA | ALDH1A1 2725/4885CHRM5 4247/4885CHRM1 3980/4885 |
| US-10428092-B2 | Process of producing phosphinothricin employing nitrilases | NPEPPS, NISCH, NAAA | ALDH1A1 2725/4885CHRM5 4247/4885CHRM1 3980/4885 |
| US-20150239917-A1 | Process of Producing Phosphinothricin Employing Nitrilases | NPEPPS, NISCH, NAAA | ALDH1A1 2725/4885CHRM5 4247/4885CHRM1 3980/4885 |
| US-20130204031-A1 | PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES | NPEPPS, NISCH, NAAA | ALDH1A1 2725/4885CHRM5 4247/4885CHRM1 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.