Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 6/20 | 0.36 |
| ▸ | GIPR | P48546 | 4/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827400 | 0.83 | SRD5A1 (0.40) | SRD5A1SRD5A2 | |
| SCHEMBL1466239 | 0.81 | GCGR (0.45) | GCGRGIPR | |
| SCHEMBL17241713 | 0.80 | GCGR (0.36) | MAPTNPC1RAB9AGCGRGIPR | |
| SCHEMBL192338 | 0.79 | RAB9A (0.48) | RAB9A | |
| SCHEMBL23357733 | 0.79 | GCGR (0.37) | GCGRGIPRSRD5A1SRD5A2 | |
| SCHEMBL1465997 | 0.79 | GCGR (0.38) | GCGRGIPRSRD5A1SRD5A2 | |
| SCHEMBL17241392 | 0.78 | NPC1 (0.38) | MAPTNPC1RAB9AGCGRGIPR | |
| SCHEMBL18497279 | 0.75 | ACHE (0.40) | SRD5A1SRD5A2 | |
| SCHEMBL3530897 | 0.74 | KDM4C (0.39) | RAB9A | |
| SCHEMBL3536252 | 0.74 | ALDH1A1 (0.37) | MAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128299-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | WO | disclosed |