Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580163 | 0.79 | ALDH1A1 (0.59) | TSHRALDH1A1MAPTMEN1KMT2A | |
| Bucrylate SCHEMBL168360 | 0.77 | TSHR (0.62) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5605430 | 0.76 | TSHR (0.63) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2530416 | 0.76 | TSHR (0.42) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5089974 | 0.76 | TSHR (0.63) | TSHRALDH1A1 | |
| SCHEMBL1473219 | 0.76 | TSHR (0.63) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL24029331 | 0.75 | TSHR (0.61) | TSHRALDH1A1 | |
| SCHEMBL1521320 | 0.75 | TSHR (0.61) | TSHRALDH1A1THRB | |
| SCHEMBL27976578 | 0.75 | TSHR (0.61) | TSHRALDH1A1 | |
| SCHEMBL11781459 | 0.74 | TSHR (0.36) | TSHRALDH1A1MEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048042-B2 | Medical articles incorporating surface capillary fiber | MEDTRONIC VASCULAR, INC. (US) | 2011-11-01 | — | — | US | disclosed |
| US-20050021152-A1 | Medical articles incorporating surface capillary fiber | MEDTRONIC, INC. | 2005-01-27 | — | — | US | disclosed |
| US-20020173770-A1 | Adhesive delivery system | ST. JUDE MEDICAL, INC. | 2002-11-21 | — | — | US | disclosed |
| EP-1146917-A1 | MEDICAL ADHESIVES | ST. JUDE MEDICAL, INC. (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043050-A1 | MEDICAL ADHESIVES | ST. JUDE MEDICAL, INC. (US) | 2000-07-27 | — | — | WO | disclosed |