Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227483 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1KMT2ACYP2C9 | |
| SCHEMBL3871222 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ACYP2C9 | |
| SCHEMBL18327114 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRMEN1KMT2ACYP2C9 | |
| SCHEMBL11781459 | 0.79 | TSHR (0.36) | ALDH1A1TSHRMEN1KMT2AMCL1 | |
| SCHEMBL2576522 | 0.79 | TSHR (0.55) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL2580189 | 0.78 | — | — | |
| SCHEMBL1739415 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1KMT2ACYP2C9 | |
| SCHEMBL29229764 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRMEN1KMT2ACYP2C9 | |
| SCHEMBL10204622 | 0.78 | TSHR (0.38) | ALDH1A1TSHRMCL1 | |
| SCHEMBL30134430 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257393-A1 | MACROMOLECULE-SUPPORTED THIENOAZEPINE COMPOUNDS, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | US | disclosed |
| US-11654199-B2 | Thienoazepine immunoconjugates, and uses thereof | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-11186011-B2 | Method for producing thermally crosslinkable polymers in a planetary roller extruder | ENTEX RUST & MITSCHKE GMBH (DE) | 2021-11-30 | — | — | US | disclosed |
| US-20200055214-A1 | Method for Producing Thermally Crosslinkable Polymers in a Planetary Roller Extruder | ENTEX RUST & MITSCHKE GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
| CN-108368220-A | Reactive resins made from renewable sources | 汉高知识产权控股有限责任公司 | 2018-08-03 | — | — | CN | disclosed |
| US-9655904-B2 | Substituted benzoazepines as toll-like receptor modulators | VENTIRX PHARMACEUTICALS, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20160137608-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160129010-A1 | Substituted Benzoazepines as Toll-Like Receptor Modulators | VENTIRX PHARMACEUTICALS INC (US) | 2016-05-12 | — | — | US | disclosed |
| US-9242964-B2 | Substituted benzoazepines as toll-like receptor modulators | VENTIRX PHARMACEUTICALS, INC. (US) | 2016-01-26 | — | — | US | disclosed |
| US-9126940-B2 | Substituted benzoazepines as toll-like receptor modulators | VENTIRX PHARMACEUTICALS, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| CN-101848565-A | Heated area element | TESA SE | 2010-09-29 | — | — | CN | disclosed |
| EP-1998222-A2 | Coating compositions | Rohm and Haas Electronic Materials LLC (US) | 2008-12-03 | — | — | EP | disclosed |
| US-20080248331-A1 | Coating composition | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-10-09 | — | — | US | disclosed |
| CN-1691936-A | Combined immediate release and extended release analgesic composition | ENDO PHARMACEUTICALS INC (US) | 2005-11-02 | — | — | CN | disclosed |
| US-20050192309-A1 | Method of preventing abuse of opioid dosage forms | PALERMO PHILIP J (US) | 2005-09-01 | — | — | US | disclosed |
| US-20050021152-A1 | Medical articles incorporating surface capillary fiber | MEDTRONIC, INC. | 2005-01-27 | — | — | US | disclosed |
| US-20020173770-A1 | Adhesive delivery system | ST. JUDE MEDICAL, INC. | 2002-11-21 | — | — | US | disclosed |
| EP-1146917-A1 | MEDICAL ADHESIVES | ST. JUDE MEDICAL, INC. (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043050-A1 | MEDICAL ADHESIVES | ST. JUDE MEDICAL, INC. (US) | 2000-07-27 | — | — | WO | disclosed |
| US-4032597-A | GRAFT POLYMER OF AN ACRYLONITRILE AND AN ACRYLIC ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137608-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | TLR8, TLR1, TLR7 | ALDH1A1 1667/4885TSHR 2731/4885MEN1 4256/4885 |
| US-20160129010-A1 | Substituted Benzoazepines as Toll-Like Receptor Modulators | TLR8, TLR7, TLR9 | ALDH1A1 2553/4885TSHR 2218/4885MEN1 4503/4885 |
| US-11654199-B2 | Thienoazepine immunoconjugates, and uses thereof | ICOS, CYP3A5, TPH1 | ALDH1A1 200/4885TSHR 623/4885MEN1 1637/4885 |
| US-20230257393-A1 | MACROMOLECULE-SUPPORTED THIENOAZEPINE COMPOUNDS, AND USES THEREOF | HTR3D, PNMT, HTR3B | ALDH1A1 202/4885TSHR 1249/4885MEN1 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.