Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | DGKG | P49619 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525344 | 0.90 | HTR2A (0.69) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| SCHEMBL6525350 | 0.90 | HTR2A (0.69) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| SCHEMBL3429384 | 0.90 | HTR2A (0.69) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| Altanserin SCHEMBL30136526 | 0.81 | HTR2A (1.00) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| Altanserin SCHEMBL404849 | 0.81 | HTR2A (1.00) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| Altanserin SCHEMBL30136524 | 0.81 | HTR2A (1.00) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| Altanserin SCHEMBL12629110 | 0.81 | HTR2A (1.00) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| SCHEMBL13904312 | 0.81 | ACHE (0.58) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| SCHEMBL22738404 | 0.80 | KDM4E (0.60) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 | |
| Altanserin SCHEMBL15662949 | 0.80 | HTR2A (1.00) | HTR2ACYP1A2CYP3A4HTR1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201186-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-29 | — | — | US | disclosed |
| US-20230148194-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148194-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | DGKK, DGKG, DGKA | HTR2A 4352/4885CYP1A2 2696/4885CYP3A4 3174/4885 |
| US-20230201186-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | DGKK, DGKG, DGKA | HTR2A 4352/4885CYP1A2 2696/4885CYP3A4 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.