Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 14/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25767141 | 0.80 | MAPT (0.42) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL20565606 | 0.78 | RIPK1 (0.39) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29208723 | 0.73 | SMN1; SMN2 (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL14338319 | 0.72 | CYP2C19 (0.48) | OPRK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23412602 | 0.70 | MEN1 (0.52) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL27031420 | 0.70 | GAA (0.49) | KDM4EALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL30790318 | 0.70 | GAA (0.49) | KDM4EALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL5025161 | 0.70 | MAPT (0.51) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL31583655 | 0.69 | OPRK1 (0.44) | OPRK1ACACB | |
| SCHEMBL30754934 | 0.69 | KMT2A (0.54) | ACACBKDM4EALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |