SCHEMBL1870774

SCHEMBL1870774

COC(=O)/C=C/CC(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.55
KEAP1 Q14145 1/20 0.55
NFE2L2 Q16236 1/20 0.55
TSHR P16473 4/20 0.42
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
HSD17B10 Q99714 2/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
TTR P02766 1/20 0.36
APP P05067 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
TYR P14679 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212257 1.00 HCAR2 (0.55) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL26699378 1.00 HCAR2 (0.55) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL14678926 0.85 HCAR2 (0.48) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL27761598 0.83 GAA (0.48) HCAR2KEAP1NFE2L2MGAMGAA
SCHEMBL13405605 0.83 MAPT (0.50) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL869080 0.82 TSHR (0.53) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL869082 0.82 TSHR (0.53) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL821076 0.82 TSHR (0.53) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL14287527 0.81 HCAR2 (0.46) HCAR2KEAP1NFE2L2TSHRCYP4F2
SCHEMBL19730845 0.81 HCAR2 (0.55) HCAR2KEAP1NFE2L2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP disclosed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP disclosed
US-12479826-B2 Pyridazinyl amino derivatives as ALK5 inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2025-11-25 US disclosed
EP-4584243-B1 CROSSLINKERS HEMOTEQ AG (DE) 2025-11-05 EP disclosed
EP-4584244-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584243-A1 CROSSLINKERS Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584245-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
US-20250163043-A1 CDK9 INHIBITOR AND USE THEREOF TRANSTHERA SCIENCES (NANJING), INC. (CN) 2025-05-22 US disclosed
US-20250134869-A1 Pyrrolo[2,3-d]pyrimidinyl, Pyrrolo[2,3-b]pyrazinyl and Pyrrolo[2,3-d]pyridinyl Acryla-mides PFIZER INC (US) 2025-05-01 US disclosed
WO-2025056815-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES HEMOTEQ AG (DE) 2025-03-20 WO disclosed
US-20090012166-A1 Oligomers of Straight-Chain and Unbranched Fatty Acids and Drugs Containing These PLT PATENT & LICENSE TRADING S.L. (ES) 2009-01-08 US disclosed
EP-1913090-B1 SULFONIUM INITIATORS, PROCESS FOR PRODUCTION AND USE IN CATIONIC POLYMERIZABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2008-10-29 EP disclosed
US-20080200585-A1 Sulfonium Initiators, Process For Production And Use In Cationic Polymerizable Compositions SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2008-08-21 US disclosed
EP-1913090-A1 SULFONIUM INITIATORS, PROCESS FOR PRODUCTION AND USE IN CATIONIC POLYMERIZABLE COMPOSITIONS 3M Innovative Properties Company (US) 2008-04-23 EP disclosed
US-20070054139-A1 Ionomer laminates, composite articles, and processes for making the same EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US disclosed
WO-2007016295-A1 SULFONIUM INITIATORS, PROCESS FOR PRODUCTION AND USE IN CATIONIC POLYMERIZABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-02-08 WO disclosed
EP-1748057-A1 Sulfonium initiators, process for production and use in cationic polymerizable compositions 3M Innovative Properties Company (US) 2007-01-31 EP disclosed
WO-2004058254-A1 HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS PHARMACIA CORPORATION (US) 2004-07-15 WO disclosed
US-4660580-A PREFERENTIAL; LIQUID AQUEOUS PRETREATMENT; IMMISCIBLE WITH PERMANENT WAVE SOLUTION WELLA AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
US-4024272-A Tetracyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012166-A1 Oligomers of Straight-Chain and Unbranched Fatty Acids and Drugs Containing These FASN, FFAR3, FFAR2 HCAR2 26/4885KEAP1 3223/4885NFE2L2 2816/4885
US-20250134869-A1 Pyrrolo[2,3-d]pyrimidinyl, Pyrrolo[2,3-b]pyrazinyl and Pyrrolo[2,3-d]pyridinyl Acryla-mides JAK2, JAK3, JAK1 HCAR2 1906/4885KEAP1 1567/4885NFE2L2 2154/4885
US-12479826-B2 Pyridazinyl amino derivatives as ALK5 inhibitors ALK, TGFBR1, ACVR1 HCAR2 877/4885KEAP1 970/4885NFE2L2 1588/4885
US-20080200585-A1 Sulfonium Initiators, Process For Production And Use In Cationic Polymerizable Compositions KCNH1, KCNH3, CCNH HCAR2 2452/4885KEAP1 3232/4885NFE2L2 3938/4885
US-20250163043-A1 CDK9 INHIBITOR AND USE THEREOF CDK9, CDK19, CDKL1 HCAR2 3720/4885KEAP1 2195/4885NFE2L2 2689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.