SCHEMBL25768849

SCHEMBL25768849

c1ccc(-c2cccc(-c3cc(-c4ccc(-c5nc(-c6ccncc6)cc(-c6ccncc6)n5)cc4)cc(-n4c5ccccc5c5ccccc54)c3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 1/20 0.41
▸ KMT2A Q03164 8/20 0.41
▸ MAPT P10636 8/20 0.41
▸ MEN1 O00255 7/20 0.41
▸ ALDH1A1 P00352 5/20 0.41
▸ HPGD P15428 4/20 0.41
▸ NTSR1 P30989 1/20 0.41
▸ KDM4E B2RXH2 5/20 0.40
▸ LMNA P02545 3/20 0.40
▸ GLA P06280 1/20 0.40
▸ HSP90AA1 P07900 1/20 0.39
▸ NPC1 O15118 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ NPSR1 Q6W5P4 2/20 0.38
▸ GRM5 P41594 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25768911 1.00 DHODH (0.41) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL25768908 0.97 MAPT (0.43) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL25768905 0.97 MAPT (0.43) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL25768880 0.97 MAPT (0.43) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL25768878 0.97 MAPT (0.43) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL19486721 0.94 MKNK1 (0.40) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL25768860 0.94 MAPT (0.41) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL25768912 0.93 DHODH (0.40) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL25768910 0.93 DHODH (0.40) DHODHKMT2AMAPTMEN1ALDH1A1
SCHEMBL25768850 0.93 DHODH (0.40) DHODHKMT2AMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255078-A1 Light Emitting Display Device LG DISPLAY CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230255078-A1 Light Emitting Display Device LG DISPLAY CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217815-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217815-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same DBH, PRPH, NBAS DHODH 860/4885KMT2A 3578/4885MAPT 273/4885
US-20230255078-A1 Light Emitting Display Device ITGAL, MAP1LC3C, ITGB4 DHODH 2913/4885KMT2A 3248/4885MAPT 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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